In a moment of idle curiosity, I wondered whether the ancient web browser on the Nintendo 3DS would be able to display F-Droid’s website. The somewhat surprising answer: yes! Everything but the largest images (e.g. the app screenshots) loads perfectly. To give a comparison which shows why that’s impressive, consider that the 3DS browser can’t even load Wikipedia properly.
Despite being admittedly irrelevant as a use-case, I’d say that this is a good reflection on the accessibility of the F-Droid website, because it indicates that the website isn’t using any particularly complex or non-standard features that could cause issues for users.
As for running F-Droid itself on the 3DS - well, I won’t be holding my breath for that 
The other way around, however…